Lymphadenopathy is caused by proliferation of lymphocytes and/or associated monocytic/phagocytic cells (reactive or neoplastic) or by infiltration of metastatic malignant cells. Generalized lymphadenopathy is established by enlarged nodes in 2 distinct anatomic regions. The condition can be either localized (single node, group of nodes, or region) or generalized. Palpability of any lymph nodes in the supraclavicular, iliac, or popliteal regions constitutes lymphadenopathy. Lymph nodes are considered to be abnormal if one or more is 1.0 cm in diameter, or in the case of an epitrochlear node, > 0.5 cm diameter. Lymphadenopathy is enlargement of one or more lymph nodes. He returned 3 weeks later with persistent pruritic erythema in both sides of his groin and no change in the size or tenderness of the inguinal lymph nodes. The patient was treated with nystatin powder for tinea cruris. Inguinal skin KOH prep was positive for fungus. Urinalysis was normal, as were tests for gonorrhea, chlamydia, HIV, and reactive plasms regain, and herpes simplex virus titer. Physical examination, including genitalia, was normal except for palpable inguinal lymph nodes (group of 4, 0.5 to 1.0 cm on the right side and two nodes, 3.0 to 4.0 cm in diameter, on left) that were mobile and tender. He had no penile discharge, hematuria or dysuria and no fever, night sweats or weight loss. They were not painful but “tender to touch.” One week prior, he had a flu-like infection with body aches that had resolved. CHERRY, MDĬonsider how you would manage the following patient presenting with lymphadenopathy.Ī 39-year-old male truck driver presented to the urgent care clinic with a 2- to 3-week history of “swollen glands” in both sides of his groin. Most cases are benign, but be on the alert for “red flags” that could signal malignancy. Urgent message: Lymphadenopathy is a common presenting issue in urgent care.
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